Antidepressant is the term given to any type of drugs that have been created to prevent or treat depression. However, while their primary purpose is to counteract the effects of mental gloom, they are also known for having notable side effects, which may include, among many others, weight loss.

Guggulsterones are generally a combination of various isolated compounds from the Commiphora Mukul plant also referred to as Gum Guggul. Scientific studies which have been carefully planned indicate that they reduce bodyweight and this is mostly attributed to the stimulating effect which they cause on the thyroid gland responsible for controlling the metabolic rate.